Department of Medicine

Department of Medicine

  Division of Pulmonary, Allergy and Critical Care Medicine

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photo Barbara Methé, PhD

Visiting Professor of Medicine

Co-director for Basic Science, Center for Microbiome and Medicine


Phone: 412-648-7784

Office: UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
Phone: 412-648-7784
Fax: 412-624-8373
Administrative Assistant:
Amy Flaugh
Phone: 412-648-7784
Fax: 412-624-8373
Education and Training
BS, The University at Albany
MS, Environmental Engineering, Rensselaer Polytechnic Institute, 1993
PhD, Environmental Engineering, Rensselaer Polytechnic Institute, 1998
Research Interest
Dr. Methé's research focuses on microbial ecology and the relationship of the microbiome to lung disease.
For my complete bibliography, Click Here.
Selected Publications:
Tarabichi, Y, Li, K, Hu, S, Nguyen, C, Wang, X, Elashoff, D, Saira, K, Frank, B, Bihan, M, Ghedin, E, Deng, JC, Methe, BA. The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles. Microbiome. 2015; Dec 15;3(1): 74.
Strange, C, Senior, RM, Sciurba, F, O'Neal, S, Morris, A, Wisniewski, SR, Bowler, R, Hochheiser, HS, Becich, MJ, Zhang, Y, Leader, JK, Methe, BA, Kaminski, N, Sandhaus, RA. GRADS Alpha-1 Study Group. Rationale and design of the genomic research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 2015; Oct;12(10): 1551-60.
McCorrison, JM, Venepally, P, Singh, I, Fouts, DE, Lasken, RS, Methe, BA. NeatFreq: Reference-free data reduction and coverage normalization for de novo sequence assembly. BMC Bioinformatics. 2014; 15: 357.
Alekseyenko, AV, Perez-Perez, GI, De Souza, A, Strober, B, Gao, Z, Bihan, M, Li, K, Methe, BA, Blaser, MJ. Community differentiation of the cutaneous microbiota in psoriasis. Microbiome. 2013; Dec 23;1(1): 31.
Methe, BA, Lasa, I. Microbiology in the 'omics era: from the study of single cells to communities and beyond. Curr Opin Microbiol. 2013; Oct;16(5): 602-4.
Li, K, Bihan, M, Methe, BA. Analyses of the stability and core taxonomic memberships of the human microbiome. PLoS One. 2013; May 6;8(5): e63139.
Conlon, EM, Postier, BL, Methe, BA, Nevin, KP, Lovely, DR. A Bayesian model for pooling gene expression studies that incorporates co-regulation information. PLoS One. 2012; 7(12): e52137.
Sponsored Research/Activities
Title: Impact of Virome on Microbial Communities in the Respiratory Tract
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R61 HL137077
Start Year: 2017
End Year: 2022
Title: Corticosteroids for Children with Febrile Urinary Tract Infections
Role: Co-Investigator
Funding Agency: Childrens Hospital of Pittsburgh
Grant Number: R01 DK087870
Start Year: 2016
End Year: 2017
Title: Basic and Translational Studies of Cystic Fibrosis (Core A)
Role: Core Leader
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: P30 DK072506
Start Year: 2017
End Year: 2018