Department of Medicine

Department of Medicine

  Division of Endocrinology and Metabolism




Administrative/Research Office:
(412) 648-9770

Patient/Clinical Inquiries:
(412) 586-9700



Postdoctoral Scholars

Hira Ali, MD

Phone: 412-586-9700
Fax: 412-586-9726
Location: Falk Medical Building
3601 Fifth Avenue, Suite 562
Pittsburgh, PA 15213


Education and Training

Education: Allama Iqbal Medical College

Training: Internal Medicine Residency, University of Pittsburgh Medical Center

Clinical Interests
Diabetes management, thyroid, adrenal and pituitary disorders

Research Interests
Pharmacokinetics and dose-response relationship of novel insulin formulations.
Hypoglycemia and its long-term effects on cognition


Brittany Durgin, PhD

Phone: 848-459-3762
Office: E1254 Biomedical Science Tower (Starzl)
200 Lothrop Street
Pittsburgh, PA 15213


Education and Training:
Education: Bachelor of Arts in Cell Biology and Neuroscience
Rutgers University-Douglass College. 
May 2010
Master of Science in Biomedical Sciences, University of Virginia, May 2013
Doctor of Philosophy in Physiology, University of Virginia, May 2017

Training: Rutgers University: Dr. Eric Lam
University of Virginia: Dr. Jessica J. Connelly and Dr. Gary K Owens

Research Interest: Metabolic syndrome. Project focus: Determine how interactions between RPS3 and CYB5R3 influence smooth muscle cell function and responses in metabolic syndrome.

Clinical Interest: Metabolic syndrome

Selected Publications:
Durgin BG, Cherepanova OA, Gomez D, Karaoli T, Alencar GF, Butcher JT, Zhou YQ, Bendeck MP, Isakson BE, Owens GK, Connelly JJ. Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions.
Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H943-H958. Epub 2017 Mar 10. PMID:28283548. doi: 10.1152/ajpheart.00029.2017.

Durgin BG, Straub AC. Redox control of vascular smooth muscle cell function and plasticity. Lab Invest. 2018 Feb 20. [Epub ahead of print] Review. PMID:29463879. doi: 10.1038/s41374-018-0032-9.

Notable Achievements:
Basic Cardiovascular Research Training Grant   July 2011 - June 2014
University of Virginia - NIH Training Grant

 American Heart Association (AHA) Pre-doctoral Fellowship Award    July 2014 - June 2016           
University of Virginia, Mid Atlantic Affiliate Winter 2014



Lia R. Edmunds, PhD

Phone: 412-648-2164 (office)/ (412) 648-2273 (lab)
Fax: 412-648-3290
Location: BST W1026 (office)/ BST W1005A  (lab)



Education and Training
Education: Washington and Jefferson College; Children's Hospital of Pittsburgh of UPMC

Research Interests
Understanding cellular and mitochondrial-driven bioenergetics during pathological states, such as nutritional stress, obesity, and insulin resistance, at a molecular level.

Selected Publications:
Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice. Costa DK, Huckestein BR, Edmunds LR, Petersen MC, Nasiri A, Butrico GM, Abulizi A, Harmon DB, Lu C, Mantell BS, Hartman DJ, Camporez JP, O'Doherty RM, Cline GW, Shulman GI, Jurczak MJ. Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E105-16. PMID: 27166280

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856. PMID: 27105497

Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. J Biol Chem. 2016 Dec 16;291(51):26241-26251. PMID: 27738108

c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate. Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. J Biol Chem. 2014 Sep 5;289(36):25382-92. doi: 10.1074/jbc.M114.580662.  PMID: 25053415

Notable Achievements:
Oral presentation at American Diabetes Association Annual Meeting, San Diego 2017
Attended Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, Nashville 2016



Joon Young Kim, PhD

Phone: 412-692-5239
Location: 4401 Penn Ave, Faculty Pavilion 6th floor #1


Bachelor of Science, Yonsei University, Seoul, Korea, 2008
PhD, Arizona State University, 2015

Postdoctoral Associate, Children’s Hospital of Pittsburgh of UPMC, 2015-2017
T32 Postdoctoral Scholar, University of Pittsburgh, 2017-present
Primary Mentor (2015- Present): Silva Arslanian, M.D. (Richard L. Day Professor of Pediatrics
University of Pittsburgh School of Medicine)

RESEARCH INTEREST: Pathophysiology and risk factors for youth prediabetes and type 2 diabetes, polycystic ovary syndrome (PCOS) in adolescent girls, and genetic/epigenetic basis of obesity, insulin resistance, and type 2 diabetes.
T32 research project: Investigating potential mechanisms responsible for severe insulin resistance in youth vs. adults.

Kim JY, Tfayli H, Michaliszyn SF, Lee S, Arslanian S. Distinguishing Characteristics of Metabolically Healthy Versus Metabolically Unhealthy Obese Adolescent Girls with Polycystic Ovary Syndrome. Fertil Steril. 2016 Jun;105(6):1603-11. [PMID: 26921624] [PMC4893886]
Kim JY, Michaliszyn SF, Nasr A, Lee S, Tfayli H, Tamara S. Hannon KS, Fida B, Arslanian S. The Shape of the Glucose Response Curve during an Oral Glucose Tolerance Test Heralds Biomarkers of Type 2 Diabetes Risk in Obese Youth. Diabetes Care. 2016 Aug;39(8):1431-9. [PMID: 27293201] [PMC4955931]
Kim JY, Tfayli H, Michaliszyn SF, Lee S, Nasr A, Arslanian S. Anti-Mullerian Hormone in Obese Adolescent Girls with Polycystic Ovary Syndrome. J Adolesc Health. 2017 Mar;60(3):333-339. [PMID: 27998701] [PMC5326592]
Kim JY, Nasr A, Tfayli H, Bacha F, Michaliszyn SF, Arslanian S. Increased Lipolysis, Diminished Adipose Tissue Insulin Sensitivity and Impaired β-cell Function Relative to Adipose Tissue Insulin Sensitivity in Obese Youth with Impaired Glucose Tolerance (IGT). Diabetes. 2017 Dec;66(12):3085-3090. [PMID: 28887312] [PMC5697947]
Kim JY, Tfayli H, Michaliszyn SF, Arslanian S. Impaired Lipolysis, Diminished Fat Oxidation and Metabolic Inflexibility in Obese Girls with Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2018 Feb 1;103(2):546-554 [PMID: 29220530] [PMC: PMC5800835]
Arslanian S, Kim JY, Nasr A, Bacha F, Tfayli H, Lee S, Toledo F.G.S. Insulin Sensitivity Across the Lifespan from Obese Adolescents to Obese Adults with Impaired Glucose Tolerance: Who is Worse Off? Pediatr Diabetes. 2018 Mar;19(2):205-211 [PMID: 28726334]
Complete List of Published Work in my Bibliography:
Notable Achievements:
ASU Graduate Research Support program (Dissertation grant: Candidate Single Nucleotide Polymorphisms Study), 2014-2015
Endocrine Society Outstanding Abstract Award. Endocrine Society, 100th Annual Meeting and Expo, Chicago, IL. 2018. “Metabolic Inflexibility, Impaired Lipolysis and Diminished Fat Oxidation in Obese Girls with Polycystic Ovary Syndrome (PCOS).”