Department of Medicine

Department of Medicine

 Division of Renal-Electrolyte

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photo Paul M. Palevsky, MD

Professor of Medicine

Renal-Electrolyte Division

University of Pittsburgh School of Medicine

Chief, Renal Section

VA Pittsburgh Healthcare System


Phone: 412-360-3932

Office: Room 7E123 (111F-U)
VA Pittsburgh Healthcare System
Pittsburgh, PA 15240
Phone: 412-360-3932
Fax: 412-360-6130
Education and Training
BS, Northwestern University, 1979
M.D., Northwestern University, 1981
Intern and Resident, Hospital of the University of Pennsylvania, 1984
Fellow in Nephrology, University of Pennsylvania School of Medicine, 1988
Research Interest
Dr. Palevsky’s research has primarily focused on acute kidney injury and critical care nephrology. He was the study chair of the VA/NIH Acute Renal Failure Trial Network (ATN) study evaluating intensity of renal replacement therapy in critically ill patients with acute kidney injury and currently serves as co-chair of the PRESERVE trial, evaluating the comparative effectiveness of saline and bicarbonate and the efficacy of N-acetylcysteine in preventing kidney damage following angiography. He is a member of the steering committee of the EUPHRATES trial, evaluating adsorption of endotoxin using polymixin-B for the treatment of severe sepsis and was a member of the steering committee for the VA NEPHRON-D study, comparing the effectiveness of monotherapy with losartan to combination therapy with losartan and lisinopril in patients with proteinuric chronic kidney disease in type 2 diabetes mellitus.
Clinical Interest
Acute kidney injury
Chronic kidney disease
End-stage kidney disease
Continuous renal replacement therapy
Quality improvement
For my complete bibliography, Click Here.
Selected Publications:
Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RMH, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P. Intensity of renal support critically ill patients with acute kidney injury. New England Journal of Medicine. 2008; 359: 7-20.
Fried LF, Duckworth W, Zhang JH, O’Connor T, Brophy M, Emanuele N, Huang GD, McCullough PA, Palevsky PM, Seliger S, Warren SR, Peduzzi P for the VA NEPHRON-D Investigators. Design of combination angiotensin receptor blockade and angiotensin converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D). Clinical Journal of the American Society of Nephrology. 2009; 4: 361-368.
Johansen KL, Smith MW, Unruh ML, Siroka AM, O’Connor TZ, Palevsky PM. Predictors of health utility among 60-day survivors of acute kidney injury in the VA/NIH Acute Renal Failure Trial Network Study. Clinical Journal of the American Society of Nephrology. 2010; 5.
Sirsawat N, Wen X, Lee MJ, Kong L, Elder M, Carter M, Unruh M, Finkel K, Vijayan A, Ramkumar M, Paganini E, Singbartl K, Palevsky PM, Kellum JA for the BioMaRK Investigators. Urinary biomarkers predict renal recovery in critically ill patients with renal support. Clinical Journal of the American Society of Nephrology. 2011; 6: InPress.
Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W,, Leehey DJ, McCullough PA, O’Connor T, Palevsky PM, Reilly RF, Seliger AL, Warren SR, Watnick S, Peduzzi P, Guarino P, for the VA NEPHRON-D Investigator. Combined angiotensin inhibition for treatment of diabetic nephropathy. New England Journal of Medicine. 2013; 369: 1892-1903.
Green JA, Mor MK, Shields AM, Sevick MA, Arnold RM, Palevsky PM, Fine MJ, Weisbord SD. Associations of Health Literacy with Dialysis Adherence and Health Resource Utilization in Patients Receiving Chronic Hemodialysis. American Journal of Kidney Disease. 2013; 62: 73-80.
Palevsky PM, Liu KD, Brophy PD, Chawla LS, Parikh CR, Thakar CV, Tolwani AJ, Waikar SS, Weisbord, SD. KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for Acute Kidney Injury. American Journal of Kidney Diseases. 2013; 61: 649-672.
Weisbord SD, Gallagher M, Kaufman J, Cass A, Parikh CR, Chertow GM, Shunk KA, McCullough PA, Fine MJ, Mor MK, Lew RA, Huang GD, Conner TA, Brophy MT, Lee J, Soliva S,, Palevsky PM. Prevention of contrast-induced acute kidney injury: A review of published trials and the design of the Prevention of Serious Adverse Events Following Angiography (PRESERVE) trial. Clinical Journal of the American Society of Nephrology. 2013; 8: 1618-1631.
Kellum JA, Chawla LS, Keener C, Singbartl K, Palevsky PM, Pike FL, Yealy DM, Huang DT, Angus DC. The effects of alternative resuscitation strategies in acute kidney injury patients with septic shock. American Journal of Respiratory and Critical Care Medicine. 2016; 193: 281-287.
Sponsored Research/Activities
Title: Protocolized Goad-Directed Resuscitation of Septic Shock to Prevent AKI
Role: Co-Investigator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK083961
Start Year: 2010
End Year: 2016
Notable Achievements
Hayes Davis Service Award, The Renal Network, 2013
Educational Ambassador, International Society of Nephrology, 2013
Deputy Editor, Clinical Journal of the American Society of Nephrology, 2011-2016
Fellow, American College of Physicians, 1992
Fellow, American College of Chest Physicians, 1996
Fellow, American Society of Nephrology, 2004
Fellow, National Kidney Foundation, 2011
Gift of Life Award, National Kidney Foundation of the Alleghenies, 2007