Department of Medicine

Department of Medicine

 Division of Renal-Electrolyte

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photo John A Kellum, MD


Vice Chair, Department of Critical Care Medicine

Director, Center for Critical Care Nephrology


Phone: 412-647-8110

Office: 604 Scaife Hall
University of Pittsburgh
Pittsburgh, PA 15261
Phone: 412-647-8110
Fax: 412-647-8060
Research Interest
Dr. Kellum's work spans various aspects of critical care medicine but centers on sepsis and acute organ dysfunction. I have organized multidisciplinary teams of investigators to study novel approaches to the treatment of sepsis and to the understanding of the pathogenesis of acute kidney injury. Our laboratory integrates the work of epidemiology and health service research with studies of basic mechanism of disease and new methods of treatment.
For my complete bibliography, Click Here.
Selected Publications:
Nadim, M.K., Durand, F., Kellum, J.A., Levitsky, J., O'Leary, J.G., Karvellas, C.J., Bajaj, J.S., Davenport, A., Jalan, R., Angeli, P., Caldwell, S.H., Fernandez, J., Francoz, C., Garcia-Tsao, G., Gines, P., Ison, M.G., Kramer, D.J., Metha, R.L., Moreau, R., Mulligan, D. Corrigendum to "Management of the critically ill patients with cirrhosis: A multidisciplinary perspective". Journal of Hepatology. 2016.
Peng, Z.Y., Zhou, F., Kellum, J.A. Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis. Intensive Care Medicine Experimental. 2016; 4(1): 12.
Zarbock, A., Kellun, J.A. The authors reply. Critical Care Medicine. 2016; 44(7): e590-1.
Joyce, E.L., Kane-Gill, S.L., Fuhrman, D.Y., Kellum, J.A. Drug-associated acute kidney injury: who's at risk?. Pediatric Nephrology. 2016.
Liu, K.D., Vijayan, A., Rosner, M.H., Shi, J., Chawla, L.S., Kellum, J.A. Clinical adjudication in acute kidney injury studies: findings from the pivotal TIMP-2*IGFBP7 biomarker study. Nephrology Dialysis Transplantation. 2016.
Heung, M., Ortega, L.M., Chawla, L.S., Wunderink, R.G., Self, W.H., Koyner, J.L., Shi, J., Kellum, J.A., Sapphire and Topaz Investigators. Common chronic conditions do not affect performance of cell cycle arrest biomarkers for risk stratification of acute kidney injury. Nephrology Dialysis Transplantation. 2016.
Honore, P.M., Nguyen, H.B., Gong, M., Chawla, L.S., Bagshaw, S.M., Artigas, A., Shi, J., Joannes-Boyau, O., Vincent, J.L., Kellum, J.A., Sapphire and Topaz Investigators. Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis. Critical Care Medicine. 2016.
Fuhrman, D.Y., Kellum, J.A. Remote Ischemic Preconditioning in the PICU: A Simple Concept With a Complex Past. Pediatric Critical Care Medicine. 2016.
Kellum, J.A., Murugan, R. Effects of non-severe acute kidney injury on clinical outcomes in critically ill patients. Critical Care. 2016; 20(1): 159.
Rivosecchi, R.M., Kellum, J.A., Dasta, J.F., Armahizer, M.J., Bolesta, S., Buckley, M.S., Dzierba, A.L., Frazee, E.N., Johnson, H.J., Kim, C., Murugan, R., Smithburger, P.L., Wong, A., Kane Gill, S.L. Drug Class Combination-Associated Acute Kidney Injury: A Review of the Literature. Annals of Pharmacotherapy. 2016.