Office:	VA Medical Center, Suite 2A-126
	University Drive C
	Pittsburgh, PA 15240
Phone:	412-360-1688
Fax:	412-360-6312
E-mail:	nis5@pitt.edu

Education
	MD, Government Medical College, India, 1980

Training
	Internship, Montefiore University Hospital, Pittsburgh, PA, 1982
	Residency Training, St. Francis Medical Center, Pittsburgh, PA, 1984
	Infectious Diseases Fellowship, University of Pittsburgh, Pittsburgh, PA, 1987

Dr. Singh's area of research interest is opportunistic viral and fungal infections in organ transplant recipients. Her specific interests include herpes virus infections (cytomegalovirus and human herpesvirus-6) in transplant recipients. Her work in this area pertains to clinical trials to optimize antiviral prophylaxis and assess CMV-specific immune responses after transplantation. The knowledge gained from these studies has implications for elucidating the mechanistic basis for CMV disease despite current prophylactic practices and for designing immune-based therapies in the future as adjuncts to antivirals for the prevention of CMV. A key area of her research interest is invasive cryptococcosis in transplant recipients. Dr. Singh has conducted pivotal studies to assess risks, disease associations, outcomes, and immunopathogenesis as it relates to this yeast in transplant recipients. These studies have made a major contribution toward the scientific rationale for the Infectious Diseases Society of America (IDSA) and American Society of Transplantation (AST) guidelines for cryptococcus in transplantation. More recently, Dr. Singh's work has focused on characterizing immune reconstitution syndrome in organ transplant recipients with opportunistic infections and on understanding how manipulation of iatrogenic immunosuppressants has the ability to alter the host immunologic milieu, posing a risk for this poorly understood entity.

Nina Singh has approximately 30 years of hands-on experience in the management of complex cases and challenging issues in transplant recipients and candidates, and optimizing prophylactic and treatment approaches based upon evidence-based data in these hosts.

Selected Publications: