Department of Medicine

Department of Medicine

  Division of Cardiology

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photo João L Cavalcante, MD

Assistant Professor of Medicine


Phone: 412-648-6598

Office: 200 Lothrop St
Scaife Hall - S-571
Pittsburgh, PA 15213
Phone: 412-648-6598
Fax: 412-647-0568
Education and Training
MD, Federal University of Ceará, Fortaleza, Brazil, 2002
Internal Medicine Residency, Henry Ford Hospital, Detroit, MI, 2006
Chief Medical Residency, Henry Ford Hospital, Detroit, MI, 2007
Cardiovascular Diseases Fellowship, Henry Ford Hospital, Detroit, MI, 2010
Advanced Cardiovascular Imaging, Cleveland Clinic, 2012
Research Interest
Outcomes Research in Valvular Disease

Interplay of Aortic Stenosis and Comorbidities including Amyloidosis and
Pulmonary Hypertension

CMR for Valvular Disease
Clinical Interest
Dr. Cavalcante spends the majority of his clinical time at UPMC Presbyterian hospital. He cares for patients with all aspects of cardiovascular disease, in particular those with valvular heart disease. He has a special training on cardiac imaging including echocardiography (transthoracic, transesophageal, and stress), cardiac CT and MRI. He is Co-Director for the Center of Mitral Valve Disease and Imaging member for the Center of Aortic Valve Disease specializing in transcatheter valve replacement.
Educational Interest
Dr. Cavalcante is very committed to the fellowship education. In 2013, while being at UPMC for only 6 months, he received by unanimous vote the Edward I. Curtiss Outstanding Teacher Award from the cardiology fellows. Some of the feedback from fellows have included: "Dr. Cavalcante elevates the standards of our echo lab and his enthusiasm and teaching skills really improve the fellow learning experience"; "Great to work with and learn from. Always enthusiastic about teaching and explaining concepts. More than just understanding MRI, he knows clinical cardiology extensively as well and can link the two while teaching."
For my complete bibliography, Click Here.
Selected Publications:
Cavalcante JL, Rodriguez LL, Kapadia S, Tuzcu EM, Stewart WJ. Role of echocardiography in percutaneous mitral valve interventions. JACC Cardiovasc Imaging. 2012; 5(7): 733-46.
Cavalcante JL, Lalude OO, Schoenhagen P, Lerakis S. Cardiovascular Magnetic Resonance Imaging for Structural and Valvular Heart Disease Interventions. JACC Cardiovasc Interv. 2016; 9(5): 399-425.
Cavalcante JL, Rijal S, Althouse AD, Delgado-Montero A, Katz WE, Schindler JT, Crock F, Harinstein ME, Navid F, Gleason TG, Lee JS. Right Ventricular Function and Prognosis in Patients with Low-Flow, Low-Gradient Severe Aortic Stenosis. J Am Soc Echocardiogr. 2016; 29(4): 325-333.
Cavalcante JL, Marek J, Sheppard R, Starling RC, Mather PJ, Alexis JD, Narula J, McNamara D, Gorcsan J 3rd. Diastolic function improvement is associated with favourable outcomes in patients with acute non-ischaemic cardiomyopathy: insights from the multicentre IMAC-2 trial. Eur Heart J Cardiovasc Imaging. 2015; Nov 30: pii:jev311.
Cavalcante JL. Watchful waiting in aortic stenosis: are we ready for individualizing the risk assessment?. Eur Heart J. 2016; 37(8): 724-6.
Badhwar V, Smith, AJ, Cavalcante JL. A pathoanatomic approach to the management of mitral regurgitation. Trends Cardiovasc Med. 2016; 26(2): 126-34.
El-Hayek G, Benjo A, Uretsky S, Al-Mallah M, Cohen R, Bamira D, Chavez P, Nascimento F, Santana O, Patel R, Cavalcante JL. Meta-analysis of coronary computed tomography angiography versus standard of care strategy for the evaluation of low risk chest pain: are randomized controlled trials and cohort studies showing the same evidence?. Int J Cardiol. 2014; 177(1): 238-45.
Cavalcante JL, Marwick TH, Hachamovitch R, Popovic ZB, Aldweib N, Starling RC, Desai MY, Flamm SD, Kwon DH. Is there a role for diastolic function assessment in era of delayed enhancement cardiac magnetic resonance imaging? A multimodality imaging study in patients with advanced ischemic cardiomyopathy. Am Heart J. 2014; 168(2): 220-8.
Cavalcante JL, Schoenhagen P. Role of cross-sectional imaging for structural heart disease interventions. Cardiol Clin. 2013; 31(3): 467-78.
Cavalcante JL, Barboza JS, Lever HM. Diversity of mitral valve abnormalities in obstructive hypertrophic cardiomyopathy. Prog Cardiovasc Dis. 2012; 54(6): 517-22.
Sponsored Research/Activities
Title: Prospective Evaluation of MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery: MRI-MVS Study
Role: Principal Investigator
Funding Agency: Atlantic Hospital Corporation
Start Year: 2017
End Year: 2018
Title: Multicenter Prospective Core Valve Study Using Cardiac MRI for Assessment of Paravalvular Aortic Regurgitation and its Impact on LV Reverse Remodeling and Cardiovascular Outcomes
Role: Principal Investigator
Funding Agency: Medtronic
Grant Number: RES
Start Year: 2016
End Year: 2019
Title: Arterial Stiffness and Wave Reflections as Determinants of Regression of Left Ventricular Hypertrophy and Fibrosis Assessed with Cardiac MRI After Aortic Valve Replacement for Severe Aortic Stenosis
Role: Principal Investigator
Funding Agency: American College of Radiology Imaging Network
Start Year: 2013
End Year: 2015
Title: TOPAS TAVI (Registry)
Role: Co-Investigator
Funding Agency: Universite Laval
Start Year: 2014
End Year: 2019
Notable Achievements
Best Clinical Research Award for project entitled: “Cardiac Amyloidosis and Aortic Stenosis-The Convergence of Two Aging Processes”. 14th Annual Research Day (May 24th 2016). Department of Medicine, 2016
Awarded from Medtronic Inc. the Investigator Initiated Grant entitled “Multicenter Prospective CoreValve Study Using Cardiac MRI for Assessment of Paravalvular Aortic Regurgitation and its Impact on L, 2016
VMI-HVI Innovator Research Award Co-Recipient (University of Pittsburgh), 2014
EuroEcho-Imaging 2015 Highlight Session – Featured Scientific Poster (Top Score): “Importance of longitudinal dyssynchrony in low flow low gradient severe aortic stenosis patients undergoing dobutamin, 2015
Edward I. Curtiss Outstanding Teacher Award (University of Pittsburgh), 2013