|
|
Dr. Medsger’s research focuses on the epidemiology, clinical and laboratory features and natural history of systemic sclerosis (SSc) and localized forms of scleroderma (LScl), Raynaud disease and polymyositis/dermatomyositis. He and collaborators have described many serologic subsets of SSc and LScl, their distinctive clinical findings, survival and immunogenetic associations. He has developed a SSc disease severity index and has proposed criteria for the classification of early SSc. Current studies include cytokines and other soluble protein markers as SSc disease activity measures, lung transplantation, SSc in twins, childhood onset SSc and LScl and the usefulness and mechanisms of action of D-penicillamine and autologous stem cell transplantation therapy.
|