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Department of Medicine

Department of Medicine

 Division of Renal-Electrolyte

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photo Irina V Zabbarova, PhD

Email: ivz2@pitt.edu

Phone: 412-383-8771

Contact
Office: A1207 Scaife Hall
3550 Terrace St
Pittsburgh, PA 15261
 
Phone: 412-383-8771
Fax: 412-648-7197
E-mail: ivz2@pitt.edu
Education and Training
Education
PhD, Moscow State University, Department of Biophysics, 2004
MS, Moscow State University, Department of Physics, 2001
Research Interest
Dr. Zabbarova’s main research interests lie in mechanisms for the development of bladder dysfunction, especially the one caused by spinal cord injury (SCI) and pelvic organ irradiation (radiation cystitis) and examination of potential therapeutic options.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Gajewski, B., Kanai, A.J., Cardozo, L., Ikeda, Y., Zabbarova, I.V. Does our limited knowledge of the mechanisms of neural stimulation limit its benefits for patients with overactive bladder? ICI-RS 2013. Neurourology and urodynamics. 2014; 33(5): 618-21.
Ikeda, Y., Zabbarova, I.V., Birder, L.A., de Groat, W.C., McCarthy, C.J., Hanna-Mitchell, A.T., Kanai, A,J. Botulinum neurotoxin serotype A suppresses neurotransmitter release from afferent as well as efferent nerves in the urinary bladder. European urology. 2012; 62(6): 1157-64.
McCarthy, C.J., Zabbarova, I.V., Brumovsky, P.R., Roppolo, J.R., Gebhart, G.F., Kanai, A.J. Spontaneous contractions evoke afferent nerve firing in mouse bladders with detrusor overactivity. The Journal of urology. 2009; 181(3): 1459-66.
Zabbarova, I., Kanai, A. Targeted delivery of radioprotective agents to mitochondria. Molecular interventions. 2008; 8(6): 294-302.
Kanai, A., Roppolo, J., Ikeda, Y., Zabbarova, I., Tai, C., Birder, L., Griffiths, D., de Grout, W., Fry, C. Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists. American journal of physiology. Renal physiology. 2007; 292(3): F1065-72.
Kanai, A., Zabbarova, I., Ikeda, Y., Yoshimura, N., Birder, L., Hanna-Mitchell, A., de Grout, W. Sophisticated models and methods for studying neurogenic bladder dysfunction. Neurourology and urodynamics. 2011; 30(5): 658-67.
Kanai, A., Wyndaele, J.J., Andersson, K.E., Fry, C., Ikdea, Y., Zabbrova, I., De Wachter, S. Researching bladder afferents-determining the effects of ß(3) -adrenergic receptor agonists and botulinum toxin type-A. Neurourology and urodynamics. 2011; 30(5): 684-91.
Kanai, A., Zabbarova, I., Oefelein, M., Radziszewski, P., Ikeda, Y., Andersson, K.E. Mechanisms of action of botulinum neurotoxins, ß3-adrenergic receptor agonists, and PDE5 inhibitors in modulating detrusor function in overactive bladders: ICI-RS 2011. Neurourology and urodynamics. 2012; 31(3): 300-8.
Kanai, A., Fry, C., Hanna-Mitchell, A., Birder, L., Zannarova, I., Bijos, D., Ikeda, Y. Do we understand any more about bladder interstitial cells?-ICI-RS 2013. Neurourology and urodynamics. 2014; 33(5): 573-6.
Walker, K.A., Ikeda, Y., Zabbarova, I., Schaefer, C.M., Bushnell, D., De Groat, W.C., Kanai, A., Bates, C.M. Fgfr2 is integral for bladder mesenchyme patterning and function. American journal of physiology. Renal physiology. 2015; 308(8): F888-98.
Sponsored Research/Activities
Title: Role of Nitric Oxide and Superoxide in Cystitis
Role: Collaborator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK071085
Start Year: 2013
End Year: 2018
Title: PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse Bladders
Role: Research Associate
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK098361
Start Year: 2014
End Year: 2019
Title: Mechanisms/Treatments of Lower Urinary Tract Dysfunction After Spinal Cord Injury - Project 1
Role: Research Associate
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: P01 DK093424
Start Year: 2013
End Year: 2018
Notable Achievements
Award in Competitive Grant Program for Young Graduate Students, Russian Foundation for Basic Research, 2003
Member, International Continence Society (ICS), 2007-present
Research grant award from Pfizer OAB-LUTS Competitive Grants Program, 2009
Research grant award from Samuel & Emma Winters Foundation, 2009
Member, The American Society of Pharmacology and Experimental Therapeutics (ASPET), 2009-present
Ad Hoc Reviewer, Neurourology and Urodynamics, 2011-present
Member, International Consultation on Incontinence - Research Society (ICI-RS), 2011-present
Member, Society of Neuroscience, 2014-present
CURE-UAB Travel Scholarship Award, 2015