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Department of Medicine

Department of Medicine

  Division of Pulmonary, Allergy and Critical Care Medicine



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photo Georgios D Kitsios, MD, PhD

Assistant Professor of Medicine

Email: kitsiosg@upmc.edu

Phone: 412-648-7784

Contact
Office: UPMC Montefiore Hospital, NW 628
3459 Fifth Avenue
Pittsburgh, PA 15213
 
Phone: 412-648-7784
Fax: 412-624-8373
E-mail: kitsiosg@upmc.edu
Administrative Assistant:
Amy Flaugh
Address: E1140 Starzl BST 200 Lothrop Street
Pittsburgh, PA 15213
Email: flaughar@upmc.edu
Phone: 412-648-7784
Fax: 412-624-8373
Education and Training
Education
MD, Aristotle University of Thessaloniki, Greece, 2003
PhD, Genetic Epidemiology, University of Thessaly, Greece, 2009
MSc, Clinical and Translational Science, Tufts University, 2010
Training
Residency, Internal Medicine, Lahey Clinic, 2014
Fellowship, Pulmonary and Critical Care Medicine, University of Pittsburgh Medical Center, 2017
Research Interest
My translational research focuses on the development of microbial DNA sequencing-based diagnostics for pneumonia and sepsis in the intensive care unit, to improve upon major deficiencies in sensitivity and timeliness of the current culture-dependent diagnostic paradigm. My work further examines the ability to define ARDS subphenotypes from lung microbiome profiles and host innate immune response to explain the clinical heterogeneity of the syndrome and allow for better targeting of interventions. I am also interested in the impact of the gut microbiome on critical illness outcomes and the use of microbial replacement therapies with fecal transplant for the eradication of multidrug-resistant organisms in chronically critically-ill patients.
Clinical Interest
My clinical focus is on delivery of evidence-based critical care medicine across diverse critically-ill populations. I attend medical intensive care units across the UPMC system and I am also involved in provision of inpatient pulmonary consultations at the main campus and through telemedicine services.
Educational Interest
Evidence-based critical care, ventilator physiology
Publications
For my complete bibliography, Click Here.
Selected Publications:
Kitsios, GD. Translating lung microbiome profiles into the next-generation gold-standard diagnostic gold-standard of pneumonia: a clinical investigator’s perspective. mSystems. 2018; 3(2): e00153-17.
Kitsios, GD, Rojas, M, Kass, DJ, Fitch, A, Sembrat, JC, Qin, S, Veraldi, KL, Gibson, KF, Lindell, KO, Pilewski, JM, Methe, B, Li, K, McDyer, J, McVerry, BJ, Morris, A. The Microbiome in Lung Explants of Idiopathic Pulmonary Fibrosis (MiLEs-IPF): a case-control study in patients with end-stage fibrosis. Thorax. 2017; in press.
Kitsios, GD, Morowitz, MJ, Dickson, RP, Huffnagle, GB, McVerry, BJ, Morris, A. Dysbiosis in the ICU: microbiome science coming to the bedside. J Crit Care. 2017; 38: 84-91.
Kitsios, GD, Dahabreh, IJ, Callahan, S, Paulus, JK, Campagna, AC, Dargin, JM. Can we trust propensity scores in critical care? A systematic comparison with randomized clinical trials. Crit Care Med. 2015; 43: 1870-9.
Kitsios, GD, Morris, A, McVerry, BJ. Antibiotic de-escalation: observational causal inference and culture-dependence. Intensive Care Medicine. 2016; 42(10): 1647-8.
Kitsios, GD, Mascari, P, Ettunsi, R, Gray, AW. Can co-administration of albumin and loop diuretics improve diuretic response in patients with hypoalbuminemia? A systematic review and meta-analysis. J Crit Care. 2014; 29(2): 253-9.
Raman, G, Moorthy, D, Hadar, N, Dahabreh, IJ, Thaler, De, Feldman, E, O'Donnell, TA, Lau, J, Kitsios, GD. Management strategies for asymptomatic carotid artery stenosis: a systematic review and meta-analysis. Ann Int Med. 2013; 158: 676-685.
Dahabreh, IJ, Sheldrick, RC, Paulus, JK, Chung, M, Varvarigou, V, Jafri, H, Rassen, JA, Trikalinos, TA, Kitsios, GD. Do observational studies using propensity score methods agree with randomized trials? A systematic comparison of studies on acute coronary syndromes. Eur Heart J. 2012; 33(15): 1893-901.
Kitsios, GD, Kent, DM. Personalised medicine: not just in our genes. BMJ. 2012; 344: e2161.
Kitsios, GD, Zintzaras, E. Genomic convergence of genome-wide investigations for complex traits. Ann Hum Genet. 2009; 73: 514-9.
Notable Achievements
NIH NHLBI K23 Career Development Award in Mentored Patient-Oriented Research, 2018
Center for Medicine and the Microbiome – award for pilot clinical trial of Fecal Microbiota Transplantation, 2017
Breathe Pennsylvania Lung Health Research Award, 2017
Best Translational research poster award, 15th Annual Research Day, Department of Medicine, University of Pittsburgh, 2017
ATS Abstract Scholarship, ATS International Conference, Washington DC 2017, 2017
ATS Abstract Scholarship, ATS International Conference, San Francisco 2016, 2016
Fellow Teaching Award of the year, Department of Medicine, University of Pittsburgh, 2015
Outstanding Resident of the Year Award, Lahey Hospital, 2014
Excellence in Medical Student Teaching Award, Tufts School of Medicine, 2013
Postgraduate Research Recognition Day, 1st award, Lahey Hospital, 2013