Department of Medicine

University of Pittsburgh

Division of Pulmonary, Allergy, and Critical Care Medicine
3459 Fifth Avenue,
628 NW
Pittsburgh, PA 15213
Academic Office: (412) 692-2210
Comprehensive Lung Center (Patient Care and Referral): (412) 648-6161

David O. Wilson, MD, MPH

Associate Professor of Medicine
Director, Georgia Cooper Memorial Lung Cancer Research Registry
Associate Director, Lung Cancer Center
UPMC Cancer Pavillion
Pulmonary Medicine
5150 Centre Ave. Ste. 4c
Pgh, PA 15232

Phone: 412-687-3355
Fax: 412-623-3303
Assistant: Rasheeda Patton
Assistant Email:


Dr. Wilson has been associated with the University of Pittsburgh Medical Center since his internship in 1980. He has been on the faculty of both the Graduate School of Public Health and the Medical School at the University of Pittsburgh in one capacity or another since 1986.  He currently is at UPMC – Shadyside and is the pulmonologist of the Multi-disciplinary Lung Cancer clinic at the Hillman Cancer Center, which he co-founded.

Clinical Interests

Dr. Wilson is the Director of the Georgia Cooper Lung Nodule/Cancer Proteomics/Genomics Research Registry and Associate Director of the Lung Cancer Center of the Hillman Cancer Center of the University of Pittsburgh Cancer Institute. He is the lead clinician for the Pittsburgh Lung cancer Screening Study (PluSS) and co-investigator for the Pittsburgh Lung Cancer SPORE.
He is the principal investigator in Pittsburgh for the Iloprost Chemo-prevention trial. He is the Director of the Nutrition Support Service at UPMC-Shadyside Hospital.  He introduced endobronchial ultrasound (EBUS) to Pittsburgh and has a longstanding interest in lung cancer staging and treatment.

Academic and Research Interests

Dr. Wilson’s research interest include: Lung Cancer screening and chemoprevention, diagnosis, staging and treatment; COPD, especially as it relates to lung cancer; Occupational Lung Diseases; General Pulmonary Medicine; and Nutrition support.

Proteomic profile of serum from lung cancer patients and controls.
Summarizes our interest in early detection and diagnosis of lung cancer.

Summary slide of data from the Pittsburgh Lung cancer Screening Study (PLuSS) showing the
relationship between lung cancer risk and Ct evidence of emphysema and PFT evidence of COPD by
by quartile of lung cancer risk.

Key Publications

Wilson DO, Weissfeld JL, Balkan A,  et al. Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Care Crit Med 2008;178:738–744.

Wilson DO, Weissfeld JL, Fuhrman CR, et al,  The Pittsburgh Lung Screening Study (PLuSS): Outcomes within 3 years of a first CT Scan. Am J Respir Crit Care Med. 2008 Jul 17. [Epub ahead of print]

PubMed Link