Department of Medicine

University of Pittsburgh

Division of Infectious Diseases

Center for Care of Infectious Diseases (CCID)
Falk Medical Building
3601 Fifth Avenue
7th Floor
Pittsburgh, PA 15213
Patient Appointments: 412-647-7228
Main CCID Fax: 412-647-7951

UPMC Mercy
1400 Locust Street
Pittsburgh, PA 15219
Patient Appointments: 412-232-5992
Fax Number: 412-232-3292

Pittsburgh Treatment and Evaluation Unit (PTEU)
PTEU Patient Appointments: 412-647-8125
PTEU Fax Number: 412-647-6253

John W. Mellors, MD


Professor of Medicine

Chief, Division Infectious Diseases

Director, HIV/AIDS Program

Office: Scaife Hall, Suite 818
3550 Terrace Street
Pittsburgh, PA 15261
Phone: 412-624-8512
Fax: 412-383-7982

BA, Dartmouth College, Hanover, NH, 1975
MD, Dartmouth Medical School, Hanover, NH, 1978

Internship/Residency Training, Yale-New Haven Hospital, New Haven, CT, 1982
Infectious Diseases Fellowship Training, Yale University School of Medicine, New Haven, CT, 1985

Area of Specialization/Research Interest  
HIV antiviral drug resistance
Microbial Trials Network (MTN)

Dr. Mellors is a tenured Professor of Medicine, Pathology, and Infectious Diseases and Microbiology, and Chief of the Infectious Diseases Division. He directs the primary care & clinical research activities in HIV/AIDS at UPMC Health System, providing care to over 1000 HIV-infected individuals.

He is the PI on the Pgh site for the Adult AIDS Clinical Trials Unit, conducting pivotal trials of new antiretrovirals, including protease inhibitors, triple drug combinations, & combination protease inhibitors.

His research as an investigator on the Multicenter AIDS Cohort Study provided insight into the relationship between viral load and disease outcome. His work in this area has helped define the genetic and biochemical basis for HIV resistance. His lab focused on the problem of HIV resistance to antiretroviral drugs & developed recombinant retroviral systems to detect drug resistant HIV.

Pittsburgh Magazine named Dr. Mellors as one of the "Best Doctors of 2012" in the May issue.

Research Link
Mellors Virology Laboratory
View Research Webpage

For Pub Med search results, click here.