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Department of Medicine

Department of Medicine

 Division of Infectious Diseases

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photo Lee H. Harrison, MD

Professor of Medicine and Epidemiology

Head, Infectious Diseases Epidemiology Research Unit

Email: lharriso@edc.pitt.edu

Phone: 412-624-1599

Contact
Office: A525 Crabtree Hall, GSPH
130 DeSoto Street
Pittsburgh, PA 15261
 
Phone: 412-624-1599
Fax: 412-624-7397
E-mail: lharriso@edc.pitt.edu
Administrative Assistant:
Jacqueline Murer
Address: Parran 507
130 DeSoto Street
Pittsburgh, PA 15261
Phone: 412-624-1599
Fax: 412-624-7397
Education and Training
Education
BA, University of Pennsylvania, Philadelphia, PA, 1978
MD, Emory University School of Medicine, Atlanta, GA, 1982
Training
Internship, University of Virginia Hospital, VA, 1985
Residency, University of Virginia Hospital, VA, 1985
Epidemic Intelligence Service Officer, Centers for Disease Control and Prevention, Meningitis and Special Pathogens Branch, 1987
Infectious Diseases Fellowship, Emory University School of Medicine, Atlanta, GA, 1989
Research Interest
Dr. Harrison is a Professor in the Infectious Disease Division and Head of the Infectious Diseases Epidemiology Research Unit. His research has focused on the epidemiology and molecular epidemiology of important bacterial pathogens, including Haemophilus influenzae, Streptococcus pneumoniae, group B Streptococcus, Neisseria meningitidis, methicillin-resistant Staphylococcus aureus, and Clostridium difficile. A major focus of his research is methods for enhanced detection of hospital-acquired transmission of bacterial pathogens. Dr. Harrison is also the Director of an NIH Fogarty International Center training grant, on the epidemiology and molecular epidemiology of serious bacterial infections and dengue in Brazil.
Clinical Interest
Dr. Harrison attends on the inpatient general infectious diseases consultation service at UPMC-Presbyterian Hospital. The service is commonly consulted for advice on diagnosis and treatment of infections including skin and soft-tissue infection; bacteremia and sepsis; central nervous system infections, such as bacterial meningitis, viral encephalitis, and brain abscess; osteomyelitis; necrotizing fasciitis; endocarditis and other cardiovascular infections; device-related and prosthetic infections; C. difficile infection; multidrug-resistant infections, and healthcare-associated infections.
Educational Interest
Dr. Harrison teaches a course entitled "Methods in Infectious Diseases Epidemiology" (EPIDEM/IDM 2161) in the Graduate School of Public Health. Topics that are covered include outbreak investigation, genomic/molecular epidemiology, new vaccines and vaccine prevention, study designs in infectious diseases epidemiology, drug-resistant bacteria, public health surveillance, and emerging infectious diseases. He also lectures on these and other topics in variety of other fora at the University of Pittsburgh, nationally, and internationally. Dr. Harrison has mentored numerous infectious diseases fellows, as well as MPH, DrPH, and PhD students.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Mustapha, MM, Marsh, JW, Krauland, MG, Fernandez, JO, de Lemos, AP, Dunning Hotopp, JC, Wang, X, Mayer, LW,, Lawrence, JG, Hiller, NL, Harrison, LH. Genomic epidemiology of hypervirulent serogroup W, ST-11 Neisseria meningitidis. EBio Medicine. 2015; 2(10): 1447-55.
Marsh, JW, Krauland, KG, Nelson, JS, Schlackman, JL, Brooks, AM, Pasculle, AW, Shutt, KA, Doi, Y, Querry, AM, Muto, CA, Harrison, LH. Genomic epidemiology of an endoscope-associated outbreak of KPC carbapenemase-producing Klebsiella pneumoniae. PLoS One. 2015; 10(12): 31044310.
Harrison, LH, Shutt, KA, Arnold, KE, Stern, EJ, Pondo, T, Kiehlbauch, JA, Myers, RA, Hollick, RA, Schmink, S, Vello, M, Stephens, DS, Messonier, NE, Mayer, L, Clark, TA. Meningococcal carriage among Georgia and Maryland high school students. Journal of Infectious Diseases. 2015; 211: 1761-1768.
Harrison, LH. Vaccines for prevention of group B meningococcal disease: Not your father’s vaccines. Vaccine. 2015; 49(6Sr): S345-S-354.
Torso, LM, Voorhees, RE, Forest, SA, Gordon, AZ, Silvestri, SA, Kissler, B, Shlackman, J, Sandt, CH, Toma, P, Bachert, J, Mertz, KJ, Harrison, LH. Escherichia coli O157:H7 outbreak associated with restaurant beef grinding. Journal of Food Protocols. 2015; 78: 1272-1297.
Curry, SR, Muto, CA, Schlackman, JL, Pasculle, AW, Shutt, KA, Marsh, JW, Harrison, LH. Use of multilocus variable number of tandem repeats analysis genotyping to determine the role of asymptomatic carriers in Clostridium difficile transmission. Clinical Infectious Diseases. 2013; 57: 1094-1102.
Sponsored Research/Activities
Title: Enhanced Detection System for Healthcare-Associated Transmission of Infection
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R01 AI127472
Start Year: 2016
End Year: 2021
Title: Analyzing Adult Pneumococcal Vaccination Implementation in the Underserved
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R01 AI116575
Start Year: 2015
End Year: 2019
Title: Genomic Epidemiology for Hospital Outbreak Detection
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI109459
Start Year: 2014
End Year: 2016
Title: Clinical Research and Mentoring in Epidemiology of Bacterial Diseases
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: K24 AI052788
Start Year: 2008
End Year: 2015
Title: Alternative Strategies for Adult Pneumococcal Vaccination
Role: Principal Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R01 AI076256
Start Year: 2008
End Year: 2013
Title: Core ABC Activities + FoodNet Active Surveillance and Audits Statewide (Admin Core)
Role: Co-Investigator
Funding Agency: Johns Hopkins University/Center for Disease Control
Grant Number: U50 CK000203
Start Year: 2012
End Year: 2016
Notable Achievements
Voting Member, Advisory Committee on Immunization Practices, CDC
Elected member, Alpha Omega Alpha Honor Medical Society
Elected member, American Society for Clinical Investigation
Elected member, American Epidemiological Society
Editorial Board, Journal of Infectious Diseases