Department of Medicine

University of Pittsburgh

Nathan Bahary, MD, PhD


Associate Professor, Department of Medicine, Division of Oncology

Associate Pofessor, Molecular Genetics and Biochemistry

Member, McGowan Institute of Regenerative Medicine

Medical Director - Pancreatic Cancer Program

Co-Director - UPMC Pancreatic Cancer Center of Excellence

Office: UPMC Cancer Pavilion
5150 Centre Avenue, 5th Floor
Pittsburgh, PA 15232
Phone: 412-864-7764
Fax: 412-648-6579
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A.B., Cornell University, 1984
M.D., Cornell University School of Medicine, 1989
Ph.D., Rockefeller University, 1992

Internship, Internal Medicine, Beth Israel Hospital-Harvard Medical School, Boston MA, 1993
Residency, Internal Medicine, Beth Israel Hospital, Harvard Medical School, Boston MA 1994-, 1995
Clinical Oncology Fellowship, Dana-Farber Cancer Institute (DFCI)/Harvard Medical School 1995-, 1998
Post-Doctoral Fellowship, Children's Hospital and DFCI/Harvard Medical School 1998-, 2003

Area of Specialization/Research Interest  
Gastrointestinal (GI) Oncology
Novel Treatment Strategies to Treat GI Cancers
Gastrointestinal Development
Development Biology using the Zebrafish model system

The principal theme of my research interests is to combine the power and insight of vertebrate development to elucidate basic molecular processes and the treatment of cancer. One of the methods used to characterize the discrete steps involved in normal vertebrate development and initiation and progression of tumors, is the generation of mutants and alteration of specific gene expression. In this regard, the zebrafish (Danio rerio) is an especially robust vertebrate system for isolating and defining the novel factors affecting these processes. The developing embryos are transparent, facilitating visualization, and have functioning organ systems by 24 hours post fertilization. Transgenic zebrafish, made by fusing the promoter elements of genes with a fluorescent marker (GFP), are being used to help elucidate the key steps in cancer development. This work will help provide the basis for designing rational, molecularly based disease directed therapies.

Lab Personnel and Web page
Dr. Carsten Stuckenholz, Dr. Ziqing Sun, Prakash Thakur, Lili Lu
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