Department of Medicine

University of Pittsburgh

Division of Endocrinology and Metabolism
200 Lothrop Street
E1140 BST
Pittsburgh, PA 15213
Administrative/Research Office: (412) 648-9770
Patient/Clinical Inquiries: (412) 586-9700

Elizaveta Menshikova, PhD

Research Associate

Office: N810 Montefiore Hospital
3459 Fifth Avenue
Pittsburgh, PA 15213
 
Phone: 412-692-2283
Fax: 412-692-2165
E-mail: evm3@pitt.edu

Education
MS, Irkuktsk State University, Russia, 1983
PhD, Moscow State University, Russia, 1995

Training
Postdoctoral Fellow, Biochemistry/Cell Biology, University of Pittsburgh, 2000

Area of Specialization/Research Interest  
Human skeletal muscle mitochondria resp. function
Effects of exercise and weight loss
Mitochondria membrane composition
mtDNA content in Type 2 diabetes & obesity
Effect of exercise on mitochondrial content and
Function in aging skeletal muscle
 

Recent Peer-Reviewed Publications
Title: Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity
Author(s): Ritov VB, Menshikova EV, Azuma K, Wood R, Toledo FG, Goodpaster BH, Ruderman NB, Kelley DE
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Volume: 298(1)
Page(s): 49-58
Title: Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
Author(s): Toledo FG, Menshikova EV, Azuma K, Radiková Z, Kelley CA, Ritov VB, Kelley DE
Year: 2008
Journal: Diabetes
Volume: 57(4)
Page(s): 987-94
Title: Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes
Author(s): Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, Kelley DE
Year: 2007
Journal: Diabetes
Volume: 56(8)
Page(s): 987-94
Title: Characteristics of skeletal muscle mitochondrial biogenesis induced by moderate-intensity exercise and weight loss in obesity
Author(s): Menshikova EV, Ritov VB, Ferrell RE, Azuma K, Goodpaster BH, Kelley DE
Year: 2007
Journal: J Appl Physiol
Volume: 103(1)
Page(s): 21-7
Title: Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome
Author(s): Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Menshikova EV, Kelley DE, Hidalgo J, Pedersen BK, Kelly M
Year: 2006
Journal: Diabetes
Volume: 55 Suppl 2
Page(s): 48-54
Title: Analysis of cardiolipin in human muscle biopsy
Author(s): Ritov VB, Menshikova EV, Kelley DE
Year: 2006
Journal: J Chromatogr B Analyt Technol Biomed Life Sci
Volume: 831(1-2)
Page(s): 63-71
Title: Effects of exercise on mitochondrial content and function in aging human skeletal muscle
Author(s): Menshikova EV, Ritov VB, Fairfull L, Ferrell RE, Kelley DE, Goodpaster BH
Year: 2006
Journal: J Gerontol A Biol Sci Med Sci
Volume: 61(6)
Page(s): 534-40
Title: Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
Author(s): Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE
Year: 2005
Journal: Diabetes
Volume: 54(1)
Page(s): 8-14
Title: Effects of weight loss and physical activity on skeletal muscle mitochondrial function in obesity
Author(s): Menshikova EV, Ritov VB, Toledo FG, Ferrell RE, Goodpaster BH, Kelley DE
Year: 2005
Journal: Am J Physiol Endocrinol Metab
Volume: 288(4)
Page(s): 818-25
Title: High-performance liquid chromatography-based methods of enzymatic analysis: electron transport chain activity in mitochondria from human skeletal muscle
Author(s): Ritov VB, Menshikova EV, Kelley DE
Year: 2004
Journal: Anal Biochem
Volume: 333(1)
Page(s): 27-38