Department of Medicine
University of Pittsburgh
Select a Division
Cardiology
Endocrinology and Metabolism
Gastroenterology, Hepatology and Nutrition
General Internal Medicine
Geriatric Medicine
Hematology/Oncology
Infectious Diseases
Pulmonary, Allergy and Critical Care Medicine
Renal-Electrolyte
Rheumatology and Clinical Immunology
Academic Resources
Home
Faculty
Fellows
Clinical Practice
Educational & Training Programs
Research
Annual Report
Make a Donation
Contact Us
Other Resources
Department of Medicine
Divisions of the Department
Internal Medicine Residency Training
Video -"Pittsburgh. A New Vision. A New Tomorrow."
Division of Endocrinology and Metabolism
200 Lothrop Street
E1140 BST
Pittsburgh, PA 15213
Administrative/Research Office: (412) 648-9770
Patient/Clinical Inquiries: (412) 586-9700
Elizaveta Menshikova, PhD
Research Associate
Office:
N810 Montefiore Hospital
3459 Fifth Avenue
Pittsburgh, PA 15213
Phone:
412-692-2283
Fax:
412-692-2165
E-mail:
evm3@pitt.edu
Education
MS, Irkuktsk State University, Russia, 1983
PhD, Moscow State University, Russia, 1995
Training
Postdoctoral Fellow, Biochemistry/Cell Biology, University of Pittsburgh, 2000
Area of Specialization/Research Interest
Human skeletal muscle mitochondria resp. function
Effects of exercise and weight loss
Mitochondria membrane composition
mtDNA content in Type 2 diabetes & obesity
Effect of exercise on mitochondrial content and
Function in aging skeletal muscle
Recent Peer-Reviewed Publications
Title:
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity
Author(s):
Ritov VB, Menshikova EV, Azuma K, Wood R, Toledo FG, Goodpaster BH, Ruderman NB, Kelley DE
Year:
2010
Journal:
Am J Physiol Endocrinol Metab
Volume:
298(1)
Page(s):
49-58
Title:
Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
Author(s):
Toledo FG, Menshikova EV, Azuma K, Radiková Z, Kelley CA, Ritov VB, Kelley DE
Year:
2008
Journal:
Diabetes
Volume:
57(4)
Page(s):
987-94
Title:
Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes
Author(s):
Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, Kelley DE
Year:
2007
Journal:
Diabetes
Volume:
56(8)
Page(s):
987-94
Title:
Characteristics of skeletal muscle mitochondrial biogenesis induced by moderate-intensity exercise and weight loss in obesity
Author(s):
Menshikova EV, Ritov VB, Ferrell RE, Azuma K, Goodpaster BH, Kelley DE
Year:
2007
Journal:
J Appl Physiol
Volume:
103(1)
Page(s):
21-7
Title:
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome
Author(s):
Ruderman NB, Keller C, Richard AM, Saha AK, Luo Z, Xiang X, Giralt M, Ritov VB, Menshikova EV, Kelley DE, Hidalgo J, Pedersen BK, Kelly M
Year:
2006
Journal:
Diabetes
Volume:
55 Suppl 2
Page(s):
48-54
Title:
Analysis of cardiolipin in human muscle biopsy
Author(s):
Ritov VB, Menshikova EV, Kelley DE
Year:
2006
Journal:
J Chromatogr B Analyt Technol Biomed Life Sci
Volume:
831(1-2)
Page(s):
63-71
Title:
Effects of exercise on mitochondrial content and function in aging human skeletal muscle
Author(s):
Menshikova EV, Ritov VB, Fairfull L, Ferrell RE, Kelley DE, Goodpaster BH
Year:
2006
Journal:
J Gerontol A Biol Sci Med Sci
Volume:
61(6)
Page(s):
534-40
Title:
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
Author(s):
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE
Year:
2005
Journal:
Diabetes
Volume:
54(1)
Page(s):
8-14
Title:
Effects of weight loss and physical activity on skeletal muscle mitochondrial function in obesity
Author(s):
Menshikova EV, Ritov VB, Toledo FG, Ferrell RE, Goodpaster BH, Kelley DE
Year:
2005
Journal:
Am J Physiol Endocrinol Metab
Volume:
288(4)
Page(s):
818-25
Title:
High-performance liquid chromatography-based methods of enzymatic analysis: electron transport chain activity in mitochondria from human skeletal muscle
Author(s):
Ritov VB, Menshikova EV, Kelley DE
Year:
2004
Journal:
Anal Biochem
Volume:
333(1)
Page(s):
27-38