Department of Medicine

University of Pittsburgh

Division of Endocrinology and Metabolism
200 Lothrop Street
E1140 BST
Pittsburgh, PA 15213
Administrative/Research Office: (412) 648-9770
Patient/Clinical Inquiries: (412) 586-9700

Robert M. O'Doherty, PhD

photo

Associate Professor of Medicine

Associate Professor of Biochemistry and Molecular Genetics

Office: E1140 Biomedical Science Tower
200 Lothrop Street
Pittsburgh, PA 15261
 
Phone: 412-648-3320
Fax: 412-648-3290
E-mail: rmo1@pitt.edu

Education
B.A., University of Dublin, 1986
PhD, Vanderbilt University, 1995

Training
Postdoctoral Fellow, Diabetes/Obesity, University of Texas, Southwestern Medical Center, 1998

Area of Specialization/Research Interest  
Understanding the causes of metabolic dysregulation in obesity/T2DM
 

Profile
The research focus of our group is the mechanisms that link obesity, insulin resistance, dyslipidemia and inflammation. We have over twenty years experience in this area, utilizing a range of metabolic, physiological, biochemical and molecular techniques in mouse and rat models, primary tissue culture, and immortal cell lines. Major foci of our current research efforts are the role of increased activity of the immune system/inflammatory pathways in the pathogenesis of the metabolic abnormalities of obesity, and metabolic cross-talk between the immune system components and peripheral tissues.

Lab Personnel and Web page
View Lab Webpage
Recent Grants
Title: Epigenomic Regulation of Gene Expression in Diet Induced Obesity
Role: Co-Investigator
Amount: $450,000
Funding Agency: NIH
Start Year: 2011
End Year: 2013
Title: Leptin Action and Macrophages
Role: PI
Amount: $1,200,000
Funding Agency: NIH
Start Year: 2011
End Year: 2015
Title: Mechanisms for Aresenic Induced Vascular Disease
Role: Co-Investigator
Amount: $180,000
Funding Agency: NIH
Start Year: 2010
End Year: 2011
Title: The Role of Myc in ChREBP-dependent Glucose-stimulated Gene Expression
Role: Co-Investigator
Amount: $900,000
Funding Agency: NIH
Start Year: 2006
End Year: 2011
Title: Lipids, Inflammatory Pathways and Insulin Resistance
Role: PI
Amount: $1,200,000
Funding Agency: NIH
Start Year: 2006
End Year: 2011

For Pub Med search results, click here.