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The research focus of our group is the mechanisms that link obesity, insulin resistance, dyslipidemia and inflammation. We have over twenty years experience in this area, utilizing a range of metabolic, physiological, biochemical and molecular techniques in mouse and rat models, primary tissue culture, and immortal cell lines. Major foci of our current research efforts are the role of increased activity of the immune system/inflammatory pathways in the pathogenesis of the metabolic abnormalities of obesity, and metabolic cross-talk between the immune system components and peripheral tissues.
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