Department of Medicine

University of Pittsburgh

Division of Endocrinology and Metabolism
200 Lothrop Street
E1140 BST
Pittsburgh, PA 15213
Administrative/Research Office: (412) 648-9770
Patient/Clinical Inquiries: (412) 586-9700

Frederick DeRubertis, MD
photo

Professor of Medicine, University of Pittsburgh School of Medicine

Vice-Chairman, Dept. of Medicine, University of Pittsburgh School of Medicine

Chief of Medicine, VA Medical Center, Pittsburgh
Office: VA Pittsburgh Healthcare System
University Drive C
Pittsburgh, PA 15240
 
Phone: 412-692-3523
Fax: 412-360-6947
E-mail: frederick.derubertis@va.gov
Education
BS, University of Pittsburgh, 1961
MD, University of Pittsburgh School of Medicine, 1965
Training
Intern, University of Pittsburgh Health Center Hospitals, 1966
Resident, University of Pittsburgh Health Center Hospitals, 1968
Chief Resident, University of Pittsburgh Health Center Hospitals, 1969
Fellowship - Endocrinology, University of Pittsburgh School of Medicine, 1970
Area of Specialization/Research Interest  
Role of eicosanoids & nitric oxide in pathogenesis of diabetic nephropathy
Role of oxidant stress in diabetic nephropathy
 
Profile
Dr. DeRubertis is the Chief of Medicine at the VA Hospital and is a Tenured Professor of Medicine and Vice Chair of Medicine at Pitt. His research focuses on the cellular mechanisms that are responsible for the renal disease (glomerulosclerosis) that occurs in patients with diabetes. His research funding is provided by a VA Merit Award and the ADA.
Recent Peer-Reviewed Publications
Title: Active care management supported by home telemonitoring in veterans with type 2 diabetes: the DiaTel randomized controlled trial
Author(s): Stone RA, Rao RH, Sevick MA, Cheng C, Hough LJ, Macpherson DS, Franko CM, Anglin RA, Obrosky DS, Derubertis FR
Year: 2010
Journal: Diabetes Care
Volume: 33(3)
Page(s): 478-84
Title: Acceleration of diabetic renal injury in the superoxide dismutase knockout mouse: effects of tempol
Author(s): DeRubertis FR, Craven PA, Melhem MF
Year: 2007
Journal: Metabolism
Volume: 56(9)
Page(s): 1256-64
Title: Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction
Author(s): DeRubertis FR, Craven PA, Melhem MF, Salah EM
Year: 2004
Journal: Diabetes
Volume: 53(3)
Page(s): 762-8
Title: Monoclonal gammopathy and spurious hypophosphatemia
Author(s): Weisbord SD, Chaudhuri A, Blauth K, DeRubertis FR
Year: 2003
Journal: Am J Med Sci
Volume: 325(2)
Page(s): 98-100
Title: Alpha-lipoic acid attenuates hyperglycemia and prevents glomerular mesangial matrix expansion in diabetes
Author(s): Melhem MF, Craven PA, Liachenko J, DeRubertis FR
Year: 2002
Journal: J Am Soc Nephrol
Volume: 13(1)
Page(s): 108-16
Title: Overexpression of manganese superoxide dismutase suppresses increases in collagen accumulation induced by culture of mesangial cells in high-media glucose
Author(s): Craven PA, Phillips SL, Melhem MF, Liachenko J, DeRubertis FR
Year: 2001
Journal: Metabolism
Volume: 50(9)
Page(s): 1043-8
Title: Overexpression of Cu2+/Zn2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice
Author(s): Craven PA, Melhem MF, Phillips SL, DeRubertis FR
Year: 2001
Journal: Diabetes
Volume: 50(9)
Page(s): 2114-25
Title: Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus
Author(s): Melhem MF, Craven PA, Derubertis FR
Year: 2001
Journal: J Am Soc Nephrol
Volume: 12(1)
Page(s): 124-33
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