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Department of Medicine

Department of Medicine

  Division of Endocrinology and Metabolism

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photo Ruya Liu, MD, PhD

Research Instructor

Email: rul36@pitt.edu

Phone: 412-648-9770

Contact
Office: 200 Lothrop Street
W1055 BST
Pittsburgh, PA 15213
 
Phone: 412-648-9770
Fax: 412-648-3290
E-mail: rul36@pitt.edu
Administrative Assistant:
Chelsea Dempsey
Address: 200 Lothrop Street
W1026 Biomedical Science Tower
Pittsburgh, PA 15213
Email: cad183@pitt.edu
Phone: 412-648-9770
Fax: 412-648-3290
Education and Training
Education
MD, Beihua University, China, 2007
PhD, Shanghai Jiaotong University, China, 2012
Training
Intern, Faculty of Medicine, Beihua University, China, 2007
Research Fellow, Massachusetts General Hospital, 2013
Postdoctoral Fellow, Houston Methodist Research Institute, 2014
Postdoctoral Associate, Baylor College of Medicine, 2015
Research Interest
Dr. Liu's research focuses broadly on understanding the etiology of endocrine and metabolic diseases. Her current studies are mainly on the function of Hippo pathway in cardiac muscle and pancreatic beta-cells. Specifically, (1)Heart disease remains the leading cause of death in the world, leading to a pressing need of discovery of nodal effectors in cardiac function. Dr. Liu has identified the non-redundant roles of Tead1, Hippo downstream transcriptional effector, in the maintenance of normal cardiac function and cardiomyocytes proliferation; (2)In line with the essential role of Hippo pathway in the regulation of tissue homeostasis, Dr. Liu expanded her research on the exploration of Hippo components in the development of pancreatic endocrine lineage specification and beta-cell maturation. The long-term goal is to identify potential therapeutic target(s) for modulating metabolism and accordingly improving public health.
Publications
Selected Publications:
Lee, J, Liu, R, deJesus, D, Kim, BS, Ma, K, Moulik, M, Yechoor, V. Circadian control of ??-cell function and stress responses. Diabetes, Obesity and Metabolism 17 (Suppl.1). 2015; 123-133.
Li, R, Buras, E, Lee, J, Liu, R, Liu, V, Espiritu, C, Ozer, K, Thompson, B, Nally, L, Yuan, G, Oka, K, Chang, B, Samson, S, Yechoor, V, Chan, L. Gene therapy with Neurogenin3, Betacellulin and SOCS-1 Reverses Diabetes in NOD Mice. Gene Therapy. 2015.
Notable Achievements
Keystone Symposia Scholarship (NHLBI)- Mitochondria, Metabolism and Heart Failure, 2015
1st Place Best Presentation, Department of Medicine Housestaff Research Symposium, Baylor College of Medicine, 2015