Department of Medicine

Department of Medicine

  Division of Cardiology

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photo John Thomas Schindler, MD

Assistant Professor of Medicine


Phone: 412-647-6296

Office: Cardiovascular Institute, UPMC Presbyterian
200 Lothrop Street, PUH, Room F-392
Pittsburgh, PA 15213
Phone: 412-647-6296
Fax: 412-647-8117
Administrative Assistant:
Lois Kmetz
Phone: 412-647-0211
Education and Training
Bachelor of Science, University of Notre Dame, 1989
MD, University of Pittsburgh, 1993
Internship - Internal Medicine, University of Pittsburgh Medical Center, 1993
Residency - Internal Medicine, National Naval Medical Center - Bethesda, 1996
Fellowship - Cardiovascular Disease, University of Pittsburgh Medical Center, 2000
Fellowship - Interventional Cardiology, University of Pittsburgh Medical Center, 2004
Research Interest
Dr. Schindler has participated in multiple national and international clinical trials which have been focused on the ideal treatment of patients with complex cardiovascular conditions. In this role, he has been published in peer reviewed journals and presented clinical findings at national cardiovascular meetings. His current clinical focus mainly centers around the individualized treatment of patients with valvular heart disease and which minimally invasive therapies are most effective.
Clinical Interest
Dr. Schindler provides comprehensive care to patients with a myriad of cardiovascular disease. He has been in clinical practice for over 10 years and has held leadership roles in various cardiac catheterization labs within the UPMC system. His current primary focus is in the treatment of complex valvular heart disease, but he also has a robust clinical practice in treating those patients with coronary and peripheral vascular disease. He has been an advocate for utilizing the radial artery when performing cardiac catheterizations in order to improve the outcomes and comfort for his patients who require such treatment. He currently sees patients at the University Center HVI office in Oakland as well as at the Downtown HVI office on Sixth Avenue. Finally, he is also heavily engaged in the treatment of those patients with the most difficult to control hypertension which is also known as resistant hypertension. He has participated in clinical trials evaluating new therapies beyond medications.
Educational Interest
Dr. Schindler has a faculty appointment within the University of Pittsburgh School of Medicine. In this role, he is involved in educating medical students, interns, residents and fellows specializing in cardiovascular disease. In addition, he is a course director of an annual Pittsburgh Conference which focuses on educations physicians on the most up to date techniques for treating patients with vascular and valvular conditions. Finally, he has organized a local Valvular Heart Disease Symposium which is sponsored by the American College of Cardiology, Pennsylvania Chapter.
For my complete bibliography, Click Here.
Selected Publications:
Cavalcante J, Althouse A, Massa R, Maddula M, Katz W, Crock F, Harinstein M, Navid F, Kliner D, Schindler J, Gleason T, Lee, JS. TCT-662 Prognostic Importance Of Pulmonary Hypertension Etiology By Invasive Hemodynamics In Patients With Severe Aortic Stenosis. Poster Presentation, San Francisco CA. 2015.
Fowler J, Gleason T, Kliner D, Forozan N, Lee JS, Schindler J. Single Center TAVR Vascular Complication Rates Using Both Self-Expanding and Balloon Expandable Valves Via Transfemoral and Left Subclavian Access Routes, Abstract 14365. Poster Presentation, Orlando FL. 2016.
Schindler J, Lee JS, Kliner D, Forozan N, Cavalcante J, Katz W, Gleason T. The Bicuspid Aortic Valve and Liver Failure. Abstract 1108. Transcatheter Valve Therapies (TVT) Oral Presentation, Chicago IL. 2016.
Gleason T, Schindler J, Adams D, Reardon M, Kleiman N, Caplan L, Conte J, Deeb GM, Hughes Jr GC, Chenowet S, Popma J. The Risk and Extent of Neurologic Events are Equivalent for High-Risk Patients Treated with Transcatheter or Surgical Aortic Valve Replacement. J Thorac Cardiovasc Surg. 2016; 1-12.
Cavalcante J, Rijal S, Althouse A, Delgado-Montero A, Katz W, Schindler J, Crock F, Harinstein M, Navid F, Gleason T, Lee JS. Right Ventricular Function and Prognosis in Patients with Low-Flow, Low-Gradient Severe Aortic Stenosis. Journal of the American Society of Echocardiography. 2016; 29(4): 325-333.
Sanchez c, Dota A, Badhwar V, Kliner D, Smith AJ, Chu D, Toma C, Wei L, Marroquin O, Schindler J, Lee JS, Mulukutla S. Revascularization heart team recommendations as an adjunct to appropriate use criteria for coronary revascularization in patients with complex coronary artery disease. Catheterization and Cardiovascular Interventions. 2015.
Cavalcante J, Rijal S, Schindler J, Gleason T, Lee JS, Schelbert E. Cardiac Amyloidosis and Aortic Stenosis – The Convergence of Two Aging Processes. Poster Presentation, Florence Italy. 2016.
Arboleda D, Hardison R, Marroquin O, Selzer F, Brooks M, Toma C, Khandhar S, Lee JS, Smith AJ, Schindler J, Scolieri S, Mulukutla S. TCT-328 Clinical Outcomes Based Upon Classification Using Appropriateness Use Criteria. Poster Presentation, San Francisco CA. 2013.
Sanchez C, Lee JS, Henry L, Chauhan C, Mulukutla S, Smith AJ, Schindler JT. Usefulness of Valvuloarterial Impedance Index Ratio to Predict Short Term Outcomes in High Risk Severe Aortic Stenosis following Balloon Aortic Valvuloplasty. Poster Presentation, San Francisco CA. 2013.
Zahr F, Anderson W, Gleason T, Navid F, Henry L, Mulukutla S, Katz W, Crock F, Lee JS, Schindler JT. TCT-824 The impact of creation of a transcatheter aortic valve program on surgical aortic valve replacement (sAVR) volume and outcomes: A single center experience. Poster Presentation, Miami FL. 2012.
Sponsored Research/Activities
Title: TAVR to Unload Left Ventricle in Patients with Advanced Heart Failure: A Randomized Trial (TAVR UNLOAD)
Role: Principal Investigator
Funding Agency: Cardiovascular Research Foundation
Start Year: 2017
End Year: 2022