Department of Medicine

Department of Medicine

 Division of Renal-Electrolyte

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photo Ghaith Noaiseh, MD

Assistant Professor of Medicine

Director. UPMC Sjögren's Clinic


Phone: 412-586-3550

Office: University of Pittsburgh, Department of Medicine
Medical Arts Building. 3708 Fifth Ave. Suite 500
Pittsburgh, PA 15213
Phone: 412-586-3550
Fax: 412-586-3540
Administrative Assistant:
Kim Reynolds
Address: 3500 terrace street
BST- S 725A
Pittsburgh, PA 15261
Phone: 412-648-9782
Fax: 412-383-8753
Education and Training
MD, Tishreen University School of Medicine, 2002
Intern, Laboratory Medicine, Tishreen University School of Medicine, 2003
Intern, Case Western Reserve/ St. Vincent Charity Hospital, 2005
Resident in Medicine. Cheif Resident, Case Western Reserve/ St. Vincent Charity Hospital, 2007
Fellow, Division of Rheumatology, University of Pennsylvania, 2012
Research Interest
Dr. Noaiseh is the site principal investigator for several randomized clinical trials assessing efficacy of different novel biological therapies in the management of Sjögren’s Syndrome and Systemic Lupus Erythematosus.
His interest is in studying how the overlap of autoimmune rheumatic diseases affects the clinical phenotype, disease course and response to therapy; specifically, the overlap of Sjögren’s Syndrome with other autoimmune diseases such as Systemic Lupus Erythematosus, myositis and Scoleroderma.
We have established UPMC Sjogren’s Registry since 2014, this aims at collecting data and blood samples of patients with Sjogren’s syndrome to facilitate research and collaboration with other institutions in this field.
Clinical Interest
I run the UPMC Sjögren's Syndrome Clinic at the UPMC Lupus Center of Excellence. The goal is to provide care to complex patients with Sjögren's Syndrome, particularly patients with extra-glandular manifestations.

Systemic Lupus Erythematosus

IgG4-Related Disease
Educational Interest
Teaching Rheumatology fellows about challenges in diagnosis and management of patients with Sjögren's syndrome

Teaching internal medicine residents and medical students about clinical reasoning in Rheumatology and key concepts in presentation and management of autoimmune Rheumatic diseases in inpatient and outpatient setting
For my complete bibliography, Click Here.
Selected Publications:
Noaiseh G, Baker JF, Vivino FB. Comparison of the discontinuation rates and side-effect profiles of pilocarpine and cevimeline for xerostomia in primary Sjogren's syndrome. Clinical and experimental Rheumatology. 2014; 32: 575-577.
Baker JF, Von Feldt J, Mostoufi-Moab S, Noaiseh G, Taratuta E, Kim W, Leonard MB. Deficits in Muscle Mass, Muscle Density, and Modified Associations With Fat in Rheumatoid Arthritis. Arthritis Care and Research. 2014; 66: 1612-1618.
Noaiseh G, Moreland LW. Current and future Biosimilars: potential practical applications in Rheumatology. Biosimilars. 2013; 3: 27-33.
St Clair W, Baer AN, Noaiseh G, Parke A, Coca A, Utset A, Genovese MC, Wallace DJ, McNamara J, Boyle K, Keyes-Elstein L. The Clinical Efficacy and Safety of Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, in Primary Sjogren's Syndrome: Results from a Randomized, Double-Blind, Placebo-Controlled Phase II Trial. Arthritis & Rheumatology. 2015; 67: Supp.
Noaiseh G, Bangle S, Vivino FB. Idiopathic Mediastinal Fibrosis Presenting With Antiphospholipid Antibody Syndrome and Manifestations Suggestive of Connective Tissue Disease. Journal of Clinical Rheumatology. 2012; 18: 146–147.
Noaiseh G, Li S, Derk C. Management of gastrointestinal manifestations in systemic sclerosis. International Journal of Clinical Rheumatology. 2012; 7: 661-673.
Sponsored Research/Activities
Title: A Multi-Center Continuation Trial of Belimumab with Systemic Lupus Erythematosus who completed the Phase 3 Protocol HGS1006-C1066 in the United States
Role: Principal Investigator
Funding Agency: Human Genome Sciences, Inc.
Grant Number: DRUG
Start Year: 2009
End Year: 2016
Title: Study for the LymphoStat-B LBSL02
Role: Principal Investigator
Funding Agency: Human Genome Sciences, Inc.
Grant Number: DRUG
Start Year: 2004
End Year: 2016
Title: Mechanisms of B Cell Responses in Autoimmune Disease: C12-ASJ02-PIT
Role: Co-Investigator
Funding Agency: Duke University/National Institute of Allergy & Infectious Diseases
Grant Number: U19 AI056363
Start Year: 2012
End Year: 2015
Notable Achievements
Consensus Panel Member, to review Clinical Practice Guidelines Draft Recommendations on rheumatological manifestations of Management and Treatment in Sjogren’s Syndrome, June 2014
Member. Americal College of Rheumatology, 2012 - Current
American College of Rheumatology Research Workshop Scholarship, Denver, Colorado., May 2012
Fellow of the year award. Division of Rheumatology. University of Pennsylvania, 2012
Resident of the year award. Internal Medicine Residency Program, Case Western Reserve University. St. Vincent Charity Hospital, 2007