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Department of Medicine

Department of Medicine

 Division of Renal-Electrolyte

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photo Nicolas Montalbetti, PhD

Email: nim71@pitt.edu

Contact
 
E-mail: nim71@pitt.edu
Research Interest
Dr. Montalbetti is examining the role of the umbrella cell layer in health and disease states. The interior of the bladder is covered by the urothelium, a stratified epithelium. Umbrella cells, the outer most cell layer in the urothelium, form an impermeable barrier that prevents the diffusion of urine constituents into the bladder interstititum. The goals of this project are to understand how umbrella cells maintain an impermeable barrier as bladders fill and deflate, and to understand how changes in urothelial permeability lead to disease states.