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Department of Medicine

Department of Medicine

  PhD Community

PhD Community Member



Members:

Nic Sluis-Cremer, PhD

Associate Professor, Infectious Diseases
Scaife Hall, Suite 817
3550 Terrace Street
Pittsburgh, PA 15261

Email: nps2@pitt.edu



Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
Will the reversal of HIV latency in resting CD4+ T cell subsets lead to a cure for HIV infection?

Can we predict response to HIV antiretroviral treatment and the transmission patterns of drug-resistant variants by studying resistance and cross-resistance pathways?

Can we develop novel antiviral or antimicrobial agents that are active against drug-resistant variants?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Antiviral and antimicrobial therapy; drug resistance; drug discovery; retrovirology; structure-function relationships

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:

Biochemical/biophysical analyses of proteins; assay development and high throughput screening; single molecule fluorescence; genotypic and phenotypic analyses of drug resistance; primary cell models of HIV latency