SCHOOL OF MEDICINE  |  PITT HOME  |  FIND PEOPLE  |  FIND A DOCTOR AT UPMC

Department of Medicine

Department of Medicine

  PhD Community

PhD Community Member



Members:

Ossama B. Kashlan, PhD

Assistant Professor, Renal-Electrolyte
S931 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261

Email: obk2@pitt.edu



Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
How do proteins in the epithelial sodium channel (ENaC) family sense their environment?

Are proteins in the ENaC family modular, i.e. do specific domains impart specific functions?

What are the biological roles of allosteric regulatory mechanisms that modulate ENaC function?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Ion channels, protein allostery, structure-function relationships, biophysics, evolution of function

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:

Electrophysiology, enzymology, molecular biology, structural modeling