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Department of Medicine

Department of Medicine

  PhD Community

PhD Community Member



Members:

Jeffrey S. Isenberg, MD, MPH, PhD

Associate Professor, PACCM
UPMC Montefiore Hospital - NW628
3459 Fifth Avenue
Pittsburgh, PA 15213

Email: jsi5@pitt.edu



Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
What are the mechanisms that control blood flow?
How are cell fate, dedifferentiation and self-renewal controlled?
What are the maladaptive mechanisms that limit tissue and organ bio-engineering?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Matrix-cellular proteins, Nitric oxide, Aging, Self-renewal and pluripotency, Drug development and translational studies, Tissue engineering

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:

Multiple models of cell and animal stress and techniques to assess tissue perfusion, blood flow and organ injury/repair
Unique global and cell-specific mutant mice
In vitro and in vivo angiogenesis assays with or without hypoxia
Rodent and human ex vivo vascular phenotyping
Nitric oxide and ROS methodologies
Tissue and organ decellularization