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Department of Medicine

Department of Medicine

  PhD Community

PhD Community Member



Members:

Lori A. Birder, PhD

Professor, Renal-Electrolyte, Pharmacology, & Chemical Biology
A1207 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261

Email: LBirder@pitt.edu



Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
Exploring the effect of aging and aging-related processes (such as changes in blood flow) on urothelial-related functional elements within the bladder wall.

Mechanisms by which chronic stress alters urothelial cell signaling resulting in augmented pain behavior.

To examine mechanisms by which urothelial cells function as mechano-sensors in the normal urinary bladder.

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Urothelial sensory function; transducer function; mechano-reciprocity; bioenergetics; extracellular matrix

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:

Primary cell culture; calcium imaging; transmitter release; mitochondrial function; molecular methods