Department of Medicine

Department of Medicine

  Division of Pulmonary, Allergy and Critical Care Medicine

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photo Seyed Mehdi Nouraie, MD, PhD

Visiting Associate Professor of Medicine


Phone: 412-648-6494

Office: UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
Phone: 412-648-6494
Fax: 412-692-4842
Administrative Assistant:
JoAnne Phillips-Kronz
Phone: 412-648-6494
Fax: 412-692-4842
Education and Training
MD, Tehran University of Medical Sciences, 1996
PhD, Epidemiology, Tehran University of Medical Sciences, 2000
Research Interest
Dr. Nouraie's outstanding skills as a biostatistician helped facilitate the development of several key studies in the area of sickle cell disease including projects on transition to adult care, predictors of pulmonary hypertension in sickle cell disease, and application of big administrative data in sickle cell disease outcome studies through data management and analysis.
His research on the design and analysis of clinical studies in the area of GI benign and malignant disease, sickle cell, and cardiovascular disorders has resulted in over 100 peer reviewed publications.
Currently he is interested in assessing the pulmonary complication of obesity and metabolic syndrome.
Educational Interest
He has been involved in teaching clinical epidemiology and study design. His education interest also includes application of biostatistical methods in causal relationships.
For my complete bibliography, Click Here.
Selected Publications:
Calhoun, G, Wang, L, Almeida, LE, Kenyon, N, Afsar, N, Nouraie, M, Finkel, JC, Quezado, ZM. Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice. Eur J Pharmacol. 2015; 754: 125-33.
Castro, O, Nouraie, M, Oneal, P. Hydroxycarbamide treatment in sickle cell disease: Estimates of possible leukaemia risk and of hospitalization survival benefit. Br J Haematol. 2014; 167(5): 687-91.
Nouraie, M, Lee, JS, Zhang, Y, Kanias, T, Zhao, X, Xiong, Z, Oriss, TB, Zeng, Q, Kato, GJ, Gibbs, JS, Hildesheim, MD, Sachdev, V, Barst, RJ, Machado, RF, Hassell, KL, Little, JA, Schraufnagel, DE, Krishnamurti, L, Novelli, E, Girgis, RE. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica. 2013; 98(3): 464-72.
Darbari, DS, Onyekwere, O, Nouraie, M, Minniti, CP, Luchtman-Jones, L, Rana, S, Sable, C, Ensing, G, Dham, N, Campbell, A, Arteta, M, Gladwin, MT, Castro, O, Taylor, JGt, Kato, GJ, Gordeuk, V. Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia. J Pediatr. 2012; 160(2): 286-90.
Nouraie, M, Nekhai, S, Gordeuk, VR. Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in U.S. hospital discharge records: A cross-sectional study. Sex Transm Infect. 2012; 88(7): 528-33.
Sachdev, V, Kato, GJ, Gibbs, JS, Barst, RJ, Machado, RF, Nouraie, M, Hassell, KL, Little, JA, Schraufnagel, DE, Krishnamurti, L, Novelli, EM, Girgis, RE, Morris, CR, Rosenzweig, EB, Badesch, DB, Lanzkron, S, Castro, OL, Taylor, JGt, Hannoush, H, Goldsmith, JC. Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom. Circulation. 2011; 124(13): 1452-60.
Nouraie, M, Reading, NS, Campbell, A, Minniti, CP, Rana, SR, Luchtman-Jones, L, Kato, GJ, Gladwin, MT, Castro, OL, Prchal, JT, Gordeuk, VR. Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia. Br J Haematol. 2010; 150(2): 218-25.
Minniti, CP, Sable, C, Campbell, A, Rana, S, Ensing, G, Dham, N, Onyekwere, O, Nouraie, M, Kato, GJ, Gladwin, MT, Castro, OL, Gordeuk, VR. Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: Association with hemolysis and hemoglobin oxygen desaturation. Haematologica. 2009; 94(3): 340-7.
Nouraie, M, Razjouyan, H, Assady, M, Malekzadeh, R, Nasseri-Moghaddam, S. Epidemiology of gastroesophageal reflux symptoms in Tehran, Iran: A population-based telephone survey. Arch Iran Med. 2007; 10(3): 289-94.
Nouraie, M, Pietinen, P, Kamangar, F, Dawsey, SM, Abnet, CC, Albanes, D, Virtamo, J, Taylor, PR. Fruits, vegetables, and antioxidants and risk of gastric cancer among male smokers. Cancer Epidemiol Biomarkers Prev. 2005; 14(9): 2087-92.
Sponsored Research/Activities
Title: Leading Emerging and Diverse Scientists to Success (LEADS)
Role: Co-Investigator
Funding Agency: National Institute of General Medical Science
Grant Number: R25 GM116740
Start Year: 2015
End Year: 2020
Title: Adiposity and Airway Inflammation in HIV-Associated Airway Disease
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: R56 HL128134
Start Year: 2015
End Year: 2016
Title: Cardiolipin as a Novel Mediator of Acute Lung Injury - Project 1
Role: Co-Investigator
Funding Agency: National Heart, Lung, & Blood Institute
Grant Number: P01 HL114453
Start Year: 2014
End Year: 2018