Department of Medicine

Department of Medicine

 Division of Infectious Diseases

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photo Jane W. Marsh, PhD


Phone: 412-648-3102

Office: Scaife Hall, Suite 865
3550 Terrace Street
Pittsburgh, PA 15261
Phone: 412-648-3102
Fax: 412-648-8455
Education and Training
PhD, Dartmouth College, 1998
BA, University of Vermont, 1982
Research Interest
Dr. Marsh is the Director of the Microbial Genomics Epidemiology Laboratory (MiGEL) and works closely with MiGEL Principal Investigator, Dr. Lee H. Harrison to investigate genomic epidemiology of hospital acquired infections. Current research is focused on integration of whole genome sequences of important multi-drug resistant bacteria from hospitalized patients with the electronic health record to enhance detection of hospital-associated transmission. MiGEL works closely with Infection Prevention to investigate genetic relationships of patient bacterial isolates suspected of being hospital acquired. Timely reporting of results enables rapid implementation of appropriate interventions to prevent further transmission and outbreaks. Other research interests include investigation of the human gut microbiome for prediction and transmission of infectious diseases as well as global genomic epidemiology and population structure of Neisseria meningitidis.
For my complete bibliography, Click Here.
Selected Publications:
Marsh, JW, Krauland, MG, Nelson, JS, Schlackman, JL, Brooks, AW, Shutt, KA, Doi, Y, Querry, AM, Muto, CA, Harrison, LH. Genomic epidemiology of an endoscope-associated outbreak of Klebsiella pneumoniae carbapenemase (KPC) –producing K. pneumoniae. PLoS One. 2015; 10(12): e:0144310.
Mustapha, MM, Marsh, JW, Krauland, MG, Gernandez, JO, de Lemos, APS, Hotopp, JCD, Wang, X, Mayer, LW, Lawrence, JG, Hiller, NL, Harrison, LH. Genomic Epidemiology of Hypervirulent Serogroup W, ST-11 Neisseria meningitidis. EBio Medicine. 2015; 8:2(10): 1447-55.
Curry, SR, Muto, CA, Schlackman, JL, Pasculle, AW, Shutt, KA, Marsh, JW, Harrison, LH. Use of Multilocus Variable Number of Tandem Repeats Analysis Genotyping to Determine the Role of Asymptomatic Carriers in Clostridium difficile Transmission. Clinical Infectious Diseases. 2013; 57(8): 1094-102.
Marsh, JW, Arora, R, Schlackman, JL, Shutt, KA, Curry, SR, Harrison, LH. Recurrent Clostridium difficile disease: Association of relapse with BI/NAP1/027. Journal of Clinical Microbiology. 2012; 50(12): 4078-82.
Marsh, JW, Shutt, KA, Pajon, R, Tulenko, MM, Liu, S, Hollick, RA, Kiehlbauch, JA, Clark, TA, Stephens, DS, Arnold, KE, Myers, RA,, Mayer, LW, Harrison, LH. Diversity of factor H-binding protein in Neisseria meningitidis carriage isolates. Vaccine. 2011; 29(35): 6049-58.
Marsh, JW, O'Leary, MM, Shutt, KA, Pasculle, AW, Johnson, S, Gerding, DN, Muto, CA, Harrison, LH. Multi-locus variable-number tandem repeat analysis for investigation of Clostridium difficile transmission in hospitals. Journal of Clinical Microbiology. 2006; 44(7): 2558-2566.
Sponsored Research/Activities
Title: Molecular Epidemiology of C. Difficile Food Contamination: Links to Human CDI
Role: Principal Investigator
Funding Agency: University of Iowa
Start Year: 2011
End Year: 2014
Title: Enhanced Detection System for Healthcare-Associated Transmission of Infection
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R01 AI127472
Start Year: 2016
End Year: 2021
Title: Genomic Epidemiology for Hospital Outbreak Detection
Role: Co-Investigator
Funding Agency: National Institute of Allergy & Infectious Diseases
Grant Number: R21 AI109459
Start Year: 2014
End Year: 2016